Tài liệu Báo cáo khoa học: Regulation of connective tissue g

Tài liệu Báo cáo khoa học: Regulation of connective tissue growth factor (CTGF/CCN2) gene transcription and mRNA stability in smooth muscle cells Involvement of RhoA GTPase and p38 MAP kinase and sensitivity to actin dynamics docx

... 2004 Regulation of connective tissue growth factor (CTGF/CCN2) gene transcription and mRNA stability in smooth muscle cells Involvement of RhoA GTPase and p38 MAP kinase and sensitivity to actin dynamics Ibrul ... the expression of the CTGF/CCN2 gene in smooth muscle cells. Keywords: actin cytoskeleton; CTGF/CCN2; p38...

Ngày tải lên : 19/02/2014, 16:20

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Tài liệu Báo cáo khoa học: Regulation of DNA fragmentation: the role of caspases and phosphorylation doc

... release of cytochrome c from mitochon- dria into the cytosol through inactivation with Bcl-xL and Bcl-2 [69]. Inactivated Bax and Bad bind 14-3-3, the phosphoserine ⁄ threonine binding proteins in ... pro-caspases are often present in the cytosol fraction (caspase-2, -3, -6, -7, -8 and -9) of living cells to separate silent precursor caspases in the cytosol from pro-apopto...

Ngày tải lên : 14/02/2014, 22:20

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Tài liệu Báo cáo khoa học: Regulation of the members of the mammalian heat shock factor family doc

... 283, 29961–29970. 107 Trinklein ND, Chen WC, Kingston RE & Myers RM (2004) Transcriptional regulation and binding of heat shock factor 1 and heat shock factor 2 to 32 human heat shock genes during thermal ... shock factors are involved in the regulation of life span and progression of cancer and they are also important for developmental processes such as gametoge...

Ngày tải lên : 18/02/2014, 04:20

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Tài liệu Báo cáo khoa học: Regulation of cathepsin B activity by 2A2 monoclonal antibody docx

... and neutral pH [22]. The latter act as competitive inhibitors, binding revers- ibly into the active site of the enzyme. Cystatins, including human cystatin C, are general inhibitors of cysteine ... which the N-terminus of the inhibitor ﬁrst binds to the enzyme, displacing the occluding loop, followed by the binding of another two loops of the inhibitor [24]. Besides protein inhi...

Ngày tải lên : 18/02/2014, 11:20

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Tài liệu Báo cáo khoa học: Regulation of dCTP deaminase from Escherichia coli by nonallosteric dTTP binding to an inactive form of the enzyme ppt

... substrate and inhibitor for binding to the same site [12]. We have previously determined the structures of wild-type dCTP deaminase in complex with dUTP and the inactive E138A mutant protein in complex ... designated A and B, originating from the A and B chains in the structure. dTTP binds at the site of the protein shown previously to bind the nucleotides dUTP and dCT...

Ngày tải lên : 18/02/2014, 16:20

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Tài liệu Báo cáo khoa học: Regulation of the actin–myosin interaction by titin doc

... conditio ns: actin alone (Actin) ; actin + T800 (Actin + T800); actin + Tm–Tn + CaCl 2 (Actin + T m-Tn); actin + Tm– Tn + T800 + CaCl 2 (Actin + Tm–Tn + T800). STOPS corres- pond to the time ﬁlaments ... ctin, M protein, C protein, MURF-1, calpain 3, myomesin, a-actinin, nebulin, telethonin and obscu rin. The elastic domains ar e made o f t andemly arranged immunoglobulin ( I...

Ngày tải lên : 19/02/2014, 16:20

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Tài liệu Báo cáo khoa học: Modulation of sterol homeostasis by the Cdc42p effectors Cla4p and Ste20p in the yeast Saccharomyces cerevisiae pptx

... plasmid combinations were spotted either onto medium lacking histidine and leucine to select for the plasmids, or onto medium lacking histidine, leucine and uracil to monitor protein interactions. ... protein–protein interaction therefore results in nongrowth on medium lacking uracil. (B) In contrast to Ste20p, Cla4p does not bind to Erg4p, Cbr1p or Ncp1p. A total of 10...

Ngày tải lên : 18/02/2014, 13:20

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Tài liệu Báo cáo khoa học: Roles of AP-2 transcription factors in the regulation of cartilage and skeletal development doc

... tumorigenesis and genetic diseases [47]. Most analyses of the regulation of AP-2 and the interactions of the transcription factor with binding partners, as well as of the regulation of target gene expression, ... chondrogenesis. Overview of the differen- tiation stages during chondrogenesis and the involvement of transcription factors (henatoxylin and eosin...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: Characterization of human deoxyribonuclease I gene (DNASE1) promoters reveals the utilization of two transcription-starting exons and the involvement of Sp1 in its transcriptional regulation ppt

... indicate intron 6 of 75 bp in fragments B and C, 3¢ portion of 35 bp in intron 5 in fragments C and D, and 3¢ portion of 25 bp in intron 6 in fragments F and I. The number at the right of each RT-PCR ... entire coding region. Thus, use of alternative promoters in DNASE1 results in no generation of protein isoforms. The 5¢-UTR of eukaryotic mRNA in uences...

Ngày tải lên : 19/02/2014, 06:20

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Tài liệu Báo cáo khoa học: Motion of the Ca2+ -pump captured ppt

... channel. This removes the troponin inhibition of the actin myosin interaction, and induces muscle contraction. When the muscle relaxes, Ca 2+ needs to be removed from the cytoplasm by the Ca 2+ -pump ... single line scan data obtained with buffer conditions. (A) Representative single line scan graphs obtained at increasing ATP concentration in the range 0–100 l M and in the p...

Ngày tải lên : 14/02/2014, 14:20

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