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Tài liệu Báo cáo khoa học: On the mechanism of action of the antifungal agent propionate Propionyl-CoA inhibits glucose metabolism in Aspergillus nidulans doc

Tài liệu Báo cáo khoa học: On the mechanism of action of the antifungal agent propionate Propionyl-CoA inhibits glucose metabolism in Aspergillus nidulans doc

Tài liệu Báo cáo khoa học: On the mechanism of action of the antifungal agent propionate Propionyl-CoA inhibits glucose metabolism in Aspergillus nidulans doc

... on glucose/ acetate /propionate as compared to glucose/ pro-pionate.Inhibition of CoASH-dependent enzymes of glucose metabolism The high levels of propionyl-CoA in the mutant strainraised the question of whether ... metabolism (Eur. J. Biochem. 271) 3231 On the mechanism of action of the antifungal agent propionate Propionyl-CoA inhibits glucose metabolism in Aspergillus nidulans Matthias Brock1and Wolfgang ... deletion strain showed significant accumulation of propionyl-CoA (Fig. 1). Addition of propionate to the glucose medium led to an increase of the propionyl-CoA level in the wild-type strain. The methylcitrate...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "On Learning Subtypes of the Part-Whole Relation: Do Not Mix your Seeds" pdf

... constraining the entity pairs participating in different types of part-whole relations. The types of part-whole relationsinstantiated by the tuples could then be determinedbased on their ontological ... these relation extraction efforts have over-looked the ontological distinctions between the different types of part-whole relations. They as-sume the existence of a single relation, subsuming the ... Learning Subtypes of the Part-Whole Relation: Do Not Mix yourSeedsAshwin IttooUniversity of GroningenGroningen, The Netherlandsr.a.ittoo@rug.nlGosse BoumaUniversity of GroningenGroningen,...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "ON THE AUTOMATIC TRANSFORMATION OF CLASS MEMBERSHIP CRITERIA" docx

... propositions whose truth must be observed in any instance satisfying the definition. Constraints on instantiation (COMPONENT2 above) are reflected in the choice of values for the instances in these ... description of the instance. This also permits easy representation of modifications to the definition, whenever the capability of inexact matching is desired. Other ways of representing definitions ... matching process. The transformation is performed by means of a process of ~ inmtRntlat~nn OF the deflnition the translation of the de/initlon f~'om a set of criteria for satisfying the...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "ON THE REPRESENTATION OF QUERY TERM RELATIONS BY SOFT BOOLEAN oPERATORS" ppt

... used for the formulation of information retrieval queries which is capable of representing both the use of compound noun phrases as well as the inclusion of synonym constructions in the query ... ori- ginally published in the C~unications of the ACM (the CACM collection), and a collection of 1460 articles in library science obtained from the Institute for Scientific Infomation (the CISI ... corresponding operator. The higher the p-value attached to an operator, the closer is the interpretation of that operator in accordance with the rules of ordinary Boolean logic. On the other...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "ON THE SYNTACTIC-SEMANTIC OF BOUND ANAPHORA ANALYSIS" potx

... phenomena in the area of pronoun binding are considered: Indirect binding of pronouns by indefinite NPs ("donkey sentences") and surface- syntactic constraints on binding ("weak cross-over"). ... pronoun binding with the ten- tative formulation of a semantic binding condition in (I): (I) ANP can bind pronouns in its scope Taken that the "scope of a NP" means the scope of ... The decision of whether a pronoun can be bound by a NP cannot be made on the basis of semantic information only. There are basically two possible ways out: On the one hand, one can pass the...
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Tài liệu Báo cáo khoa học: How to remain nonfolded and pliable: the linkers in modular a-amylases as a case study ppt

Tài liệu Báo cáo khoa học: How to remain nonfolded and pliable: the linkers in modular a-amylases as a case study ppt

... mobility of the connecting region is required at the N-terminus of the aromatic side chain.Modeling and molecular dynamics simulations In order to address the possible conformations andmotions of the ... near the N- and C-termini of the linkers: this suggests thata mobile connection with both the catalytic domainand the binding module is required for the function of the nanomachine. Furthermore, ... result in unwantedinteractions between the linker and the binding module. In this respect, 72% of the C-terminal aromatic residuesare preceded by Gly at the )3or)4 position, indicatingthat...
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Tài liệu Báo cáo khoa học: Membrane targeting and pore formation by the type III secretion system translocon pdf

Tài liệu Báo cáo khoa học: Membrane targeting and pore formation by the type III secretion system translocon pdf

... characterization of the proteinsinvolved in translocon formation, as well as their participation in the modi-fication of intracellular signalling pathways upon infection. Models of tran-slocon assembly ... by the sug-gestion that pH sensing by Salmonella involves modi-fications in the assembly of the translocon, whichaffect the pH gradient within the needle, sending sig-nals to the base of the ... type Iinterferon) in response to a strain of Y. pseudotubercu-losis expressing a functional translocation pore but notafter the introduction of T3SS toxins into the cellsindependently of pore...
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Tài liệu Báo cáo khoa học: Multifunctional host defense peptides: Antimicrobial peptides, the small yet big players in innate and adaptive immunity docx

Tài liệu Báo cáo khoa học: Multifunctional host defense peptides: Antimicrobial peptides, the small yet big players in innate and adaptive immunity docx

... thatb-defensins participate in the triggering of an immuneresponse and in the natural process of elimination of activated antigen-presenting cells and termination of the immune response [90].HealingInfection ... an in ammatory disease of the small intestine and ⁄ or the colon. As mentionedalready, in the small intestine, the pathogenesis is asso-ciated with a reduced expression of the Wnt signalingpathway ... angiogenesis[94]. Consistent with this role in wound healing, and in addition to increased bacterial colonization, mice lack-ing the cathelicidin gene have longer periods of woundhealing than their wild-type...
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Tài liệu Báo cáo khoa học: Molecular and cellular specificity of post-translational aminoacyl isomerization in the crustacean hyperglycaemic hormone family docx

Tài liệu Báo cáo khoa học: Molecular and cellular specificity of post-translational aminoacyl isomerization in the crustacean hyperglycaemic hormone family docx

... Axon terminal containingD-Trp4 VIH. (G) Two neighbouring axon terminals, one containing D-Trp4 VIH and the other D-Phe3 CHH. (H, I)Higher magnifications of D-Trp4 VIH and D-Phe3 CHH containing ... terminal in the sinus gland, as a result of late and progressiveisomerization of the Phe3 of the CHH during the migration of the secretion vesicles along the axonaltract [39,41]. The immunohistochemical ... in the crayfish Orconectes limosus,showing that l-isomer of CHH is always present in the different parts of the d-CHH cells, in decreasingamounts from the cell body to the axon terminal in the...
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Tài liệu Báo cáo khoa học: Olfactory receptor signaling is regulated by the post-synaptic density 95, Drosophila discs large, zona-occludens 1 (PDZ) scaffold multi-PDZ domain protein 1 pptx

Tài liệu Báo cáo khoa học: Olfactory receptor signaling is regulated by the post-synaptic density 95, Drosophila discs large, zona-occludens 1 (PDZ) scaffold multi-PDZ domain protein 1 pptx

... light on the function of this interaction in the in vivo situation.By in uencing the duration of the Ca2+signal of ORs in the cilia of the sensory neurons, MUPP1 couldhave a strong in uence on ... 30% of receptors contain putative PDZbinding motifs in their C-termini, following the previ-ously outlined rules of binding [16]. PDZ domains1 + 2 of MUPP1 indeed showed direct interactionwith ... phosphorylation, ultimately result-ing in deactivation of the channel [12,29,30]. On the other hand, in contrast to the findings of the presentstudy, MUPP1 was shown to prolong the duration of GABABreceptor...
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