... from the findings of the literature reviewed, including person and disease/treatment.PersonPerson variables that contribute to the rising incidence of chronic GVHD include older age of recipients ... cells can initiate a response against autoantigens leading to B-cell hyperre-activity and production of autoantibodies, causing target-organ damage, including skin, mucosa, eyes, joints, and liver ... rash and itching may occur; the skin may become scaly; the skin may heal by scarring; hair loss may accompany the skin injuryEyes and mouth Look for dry eyes: no tears, constant rubbing and blinking;...