Tài liệu Báo cáo khoa học: Salt-induced formation of the A-state of ferricytochrome c – effect of the anion charge on protein structure docx

Tài liệu Báo cáo khoa học: EGF receptor in relation to tumor development: molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors docx

Tài liệu Báo cáo khoa học: EGF receptor in relation to tumor development: molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors docx

... enhance anticancer drug activity. Our recent results have shown that the activation of JNK induced by EGFR-TKI AG1478 is critical for the apoptotic action of AG1478 against the NSCLC cell line PC-9 ... Members of the KIP family can inhibit the catalytic activity of CDK2, 4 and 6 Members of the INK4 family are speci c inhibitors of the cyclin D–CDK4 ⁄ 6 complex It is...
Ngày tải lên : 16/02/2014, 09:20
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Tài liệu Báo cáo khoa học: Hepatic stimulator substance mitigates hepatic cell injury through suppression of the mitochondrial permeability transition pdf

Tài liệu Báo cáo khoa học: Hepatic stimulator substance mitigates hepatic cell injury through suppression of the mitochondrial permeability transition pdf

... analyzed using cellquest software (Becton Dickinson). Isolation of mitochondria The isolation of mitochondria was performed according to the instructions for the Mitochondria ⁄ Cytosol Isolation Kit for Cultured ... to protons and causes dissi- pation of the proton gradient across the IM. CCCP also uncouples the transfer of electrons through the electron transfer chain f...
Ngày tải lên : 16/02/2014, 09:20
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Tài liệu Báo cáo khoa học: Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo pptx

Tài liệu Báo cáo khoa học: Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo pptx

... Diagnostics) and the following PCR primer sets: 5¢-GGAGATCTCCAGTGA TATCGACCA-3¢ and 5¢-ACGGCTTCTACGGATCGAA ACT-3¢ for PPARc ,5¢-AAGACAGCTCCTCCTCGAAGG TT-3¢ and 5¢-TGACCAAATCCCCATTTACGC-3¢ for ... aP2, 5¢-ATCCATGGATGGACGGTAACG-3¢ and 5¢-CTGGA TCCCAATACTTCGACCA-3¢ for LPL, 5¢-TGGGTTGG CTGCTTGTG-3¢ and 5¢-GCGTGGGCAGGATGAAG-3¢ for SCD, 5¢-GATGTGGAACCCATAACTGGATTCAC-3¢ and 5¢-GGTCCCAGTCTCATTTAGC...
Ngày tải lên : 16/02/2014, 09:20
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Tài liệu Báo cáo khoa học: Simplified yet highly accurate enzyme kinetics for cases of low substrate concentrations ppt

Tài liệu Báo cáo khoa học: Simplified yet highly accurate enzyme kinetics for cases of low substrate concentrations ppt

... example of this phenomenon is offered by an enzyme-catalyzed reaction where the function is the conversion of one metabolite into another: in this case, the formation and dispersion of the complex of the ... The concentrations of the molecules depicted in boxes are the state variables in the model [8], whereas the concentrations of the remaining molecules a...
Ngày tải lên : 18/02/2014, 06:20
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Tài liệu Báo cáo khoa học: a-Defensins increase lung fibroblast proliferation and collagen synthesis via the b-catenin signaling pathway doc

Tài liệu Báo cáo khoa học: a-Defensins increase lung fibroblast proliferation and collagen synthesis via the b-catenin signaling pathway doc

... in the culture medium, which corresponds to changes in intracellular collagen-I protein content. In addition, quercetin prevented an a-defensin-induced increase in collagen content in the culture ... image of immunoblot against active ⁄ dephosphorylated b-catenin from three experiments. WO siRNA Control siRNA β-catenin siRNA Con D1 D2 Con D1 D2 Con D1 D2 Con D1 D2 Con D1 D2 Con D1 D2...
Ngày tải lên : 18/02/2014, 06:20
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Tài liệu Báo cáo khoa học: Arabidopsis thaliana BTB⁄ POZ-MATH proteins interact with members of the ERF⁄AP2 transcription factor family ppt

Tài liệu Báo cáo khoa học: Arabidopsis thaliana BTB⁄ POZ-MATH proteins interact with members of the ERF⁄AP2 transcription factor family ppt

... interac- A B 347150381203 442 BTBHTAMBPM1 189 1–1 51 F RAP2.4 1 150 214 AP2 334 60 12 5–2 51 C D BPM1 BPM1 1–1 51 BPM1 1–1 89 GST GST:RAP2.4 – – – – ++ + – – –+ – – + BPM1 T7 input BPM1 1–1 51 BPM1 1–1 89 –+ – +– – + –+ GST GST:BPM1 T7 input RAP2.4 1–2 51 RAP2.4 1–2 51 RAP2.4 1–2 95 RAP2.4 1–2 95 E RAP2.4 G179S RAP2.4 134–...
Ngày tải lên : 18/02/2014, 06:20
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Tài liệu Báo cáo khoa học: Cobalamin uptake and reactivation occurs through specific protein interactions in the methionine synthase–methionine synthase reductase complex docx

Tài liệu Báo cáo khoa học: Cobalamin uptake and reactivation occurs through specific protein interactions in the methionine synthase–methionine synthase reductase complex docx

... of incubation at 37 C, the reaction was quenched by the addition of 0.2 mL of a solution containing 11 m formic acid and 5 m HCl, and heated to 90 C for 10 min. The acidification of the reaction mixture ... nmolÆmin )1 . (B) The dependence of hMS activity on NADPH concentration, illustrating the optimal concentration of NADPH required for reductive methylation (react...
Ngày tải lên : 18/02/2014, 08:20
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Tài liệu Báo cáo khoa học: Brain angiogenesis in developmental and pathological processes: therapeutic aspects of vascular endothelial growth factor doc

Tài liệu Báo cáo khoa học: Brain angiogenesis in developmental and pathological processes: therapeutic aspects of vascular endothelial growth factor doc

... Special Pro- ject Research on Cancer-Bioscience 17014020 from the Ministry of Education, Culture, Sports, Science and Technology of Japan, a grant from the program ‘Research for the Future’ of the ... show c- myc activation, but the dominant active mutant form of Ras is less frequent. Gene amplification and activation of EGFR occur in more than one third of cases, the...
Ngày tải lên : 18/02/2014, 11:20
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Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Potential role of ceramide metabolism in Lewy body disease pptx

Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Potential role of ceramide metabolism in Lewy body disease pptx

... iron accumulation-2 (NBIA-2) is characterized by the disruption of cellular mechanisms leading to the accumulation of iron in the basal ganglia. Mutations in the gene PLA2G6 were recently described ... been cloned in which mutations cause parkinsonism in a mendelian fashion [ 3–8 ] (Table 1). Classically, the approach taken to the study of genetic forms of PD has relied...
Ngày tải lên : 18/02/2014, 14:20
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Tài liệu Báo cáo khoa học: Hypoxic resistance to articular chondrocyte apoptosis – a possible mechanism of maintaining homeostasis of normal articular cartilage pdf

Tài liệu Báo cáo khoa học: Hypoxic resistance to articular chondrocyte apoptosis – a possible mechanism of maintaining homeostasis of normal articular cartilage pdf

... TRAIL protein for an additional 12 h under normoxic and hypoxic conditions. Hypoxic conditions inhibited significantly the apoptosis of chondrocytes induced by cotreatment of the cells with the ... carti- lage chondrocytes. Arthritis Rheum 27, 129 0–1 299. 29 Marcus RE (1973) The effect of low oxygen concentra- tion on growth, glycolysis, and sulfate incorporation by arti...
Ngày tải lên : 18/02/2014, 14:20
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