Tài liệu Báo cáo khoa học: Osmosensing and signaling in the regulation of mammalian cell function docx

... integrin-dependent cell volume sensing and signaling integrates into the overall context of insulin signaling. Similarly, sensing of glutamine-induced hepatocyte swelling by integrinsfeeds into ... MINIREVIEW Osmosensing and signaling in the regulation of mammalian cell function Freimut Schliess, Roland Reinehr and Dieter Ha¨ussingerClinic for Gastroenterology, Hepatology and Infectiology, ... cell volume to a functional outcome.This minireview summarizes recent progress in the understanding of how osmosensing and osmosignaling integrate into the overall context of growthfactor signaling...

Tài liệu Báo cáo khoa học: Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc docx

... conclusion, the identiﬁcation of new metabolites of vitamin D3 made by the action of P450scc willenable us to proceed with further biological testing of these compounds and the investigation of whether ... endocrine effects, and is also a potent antiproliferative and differentiation-inducing agent in different cell types, including epider-mal keratinocytes [7–10]. To determine whether the major ... determining the substrates from which they arose by the action of P450scc, as well as the products that they gave rise to.This revealed both the major and minor pathways for the metabolism of vitamin...

Tài liệu Báo cáo khoa học: "Some Pragmatic Issues in the Planning of Definite and Indefinite Noun Phrases" potx

... Pragmatic Issues in the Planning of Definite and Indefinite Noun Phrases Douglas E. Appelt Artificial Intelligence Center, SRI International and Center for the Study of Language and Information ... capable of distinguishing him from the other guests at the party, not to know who it really is wearing the disguise. Identification of the denotation of a term D is therefore defined as finding ... mutually know of a plan that will result in identification of the intended referent, and in the case of the S[ action, the plan is simply to do nothing, because the referent of the term is already...

Tài liệu Báo cáo khoa học: An intermediate step in the evolution of ATPases – a hybrid F0–V0 rotor in a bacterial Na+ F1F0 ATP synthase pdf

... looselyarranged, and the densities correspond to the N- and C-terminal helices of the c ring, respectively. The C-terminal helices show a clear handedness, and two of the rings face in the opposite ... represent the view from the cytoplasm (open rings in AFM) and the red ones the view from the extracellular side (smaller, closedrings in Fig. 3). The inner and outer diameters of the rings, measured ... of the ion-binding site. Therefore, the c ring of A. woodii hasonly 10 membrane-buried negative charges that areessential for binding the ion and also for the rotationalmechanism of the ring....

Tài liệu Báo cáo khoa học: "Reactive Content Selection in the Generation of Real-time Soccer Commentary" pdf

... game situation. In the Figure 5, we have illus- trated this in the same way we did for the case of interruption. The left hand side of the solid line is lower than that of the dotted because ... immediately interrupting the current ut- terance and switching to the new one. For example, the left of Figure 5 shows (solid line) the change of the importance score with time when an interruption ... memory, and then post the results as propositions into the Pool. The Real Time Inference Engine processes the propositions. Prpositions deposited in the Pool are bare facts and are often too...

Tài liệu Báo cáo khoa học: "Harnessing NLP Techniques in the Processes of Multilingual Content Management" pptx

... “processing” phase. The language processing tools are integrated in a language processing chain (LPC), so that the output of a given NLP tool is used as an input for the next tool in the chain. The ... development of deep analysis tools capable of generating abstractive summaries and training models for decision making systems. Introduction The advent of the Web revolutionized the way in which ... following the provided base-line scenarios and accompanying exercises. The main instrument for collecting user feedback is an online interactive electronic questionnaire7. The second round of...

Tài liệu Báo cáo khoa học: Applications and trends in systems biology in biochemistry docx

... acid,argininecatabolismto NO and polyaminesNG, aortaendothelialcellsLow afﬁnity transporter and arginaseshare the control of the ﬂuxesthrough the pathways involvingarginine as a precurser of nitricoxide and polyaminesODE ... 202–216.87 Choline,glycinebetainebiosynthesisNicotianatabacumImport of choline into the chloroplastis a major but not the only importantconstraint on glycine betainesynthesis. The regulation ... computationalmodeling. Here, computational modeling does notrefer to statistical models or models of data miningbut rather to a mathematical or ’virtual’ representation of the living system of interest in the...

Tài liệu Báo cáo khoa học: Enzymatic and electron paramagnetic resonance studies of anabolic pyruvate synthesis by pyruvate: ferredoxin oxidoreductase from Hydrogenobacter thermophilus doc

... coupledassay. In the presence of the reduced Fd1 and acetyl-CoA, the HE-TPP radical intermediate was formed(Figs 3F and 4B), indicating the intermediacy of the HE-TPP radical in both the oxidative and ... under-standing of the metabolism of H. thermophilus. Indeed,this would enable the kinetic analysis of the POR reac-tions in both directions. In particular, the reaction rateunder physiological intracellular ... of the [4Fe-4S]1+clusters in Fig. 3B(determined by comparing the double integrals of the EPR spectra), indicating that a substoichiometricamount of the [3Fe-4S] cluster was derived from the oxygen-sensitive...

Tài liệu Báo cáo khoa học: Diversity and junction residues as hotspots of binding energy in an antibody neutralizing the dengue virus doc

... on anti-bodies and their genes, and performed a systematicscanning of the CDR3 loops of mAb4E11 by mutagen-esis of their residues into alanine (Ala scanning). The afﬁnities of the puriﬁed mutant ... interaction(Table 1).Kinetics of the interactionTo analyse the contributions of the residues in the CDR3 loops to the kinetics of interaction between the Fab4E11-H6 fragment and its MalE-E3-H6 ... VLcontain the residues of diversity and junction,encoded by the D segment, and the VH-D, D-JH, and VL-JLjunctions [17]. They are located at the center of the antibody combining site...

Tài liệu Báo cáo khoa học: "Liars and Saviors in a Sentiment Annotated Corpus of Comments to Political debates" pdf

... definite descrip-tions and nicknames. 1 Introduction Most of the existing approaches to opinion mining propose algorithms that are independent of the text genre, the topic and the target involved. ... percentage of votes in . Polarity distribution per candidate Also interesting is the information contained in the distributions of positive opinions. We observe The Pearson corre-) between the ... prime the later achieved the lowest percentage of votes in the 2009 parliamentary election. Fig. 2. Polarity distribution per candidate Also interesting is the information contained in the...

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