Tài liệu Báo cáo khoa học: Mitogen-activated protein kinase

Tài liệu Báo cáo khoa học: Mitogen-activated protein kinase phosphatase-1 modulated JNK activation is critical for apoptosis induced by inhibitor of epidermal growth factor receptor-tyrosine kinase pdf

... in epidermal growth factor- mediated protection against apoptosis induced by a DNA-damaging agent. FEBS J 273, 3743– 3755. K. Takeuchi et al. JNK activation is critical for AG1478 -induced apoptosis FEBS ... apoptosis FEBS Journal 276 (2009) 1255–1265 ª 2009 The Authors Journal compilation ª 2009 FEBS 1265 Mitogen-activated protein kinase phosphatase-1 modul...

Ngày tải lên : 18/02/2014, 13:20

11
659
0

Tài liệu Báo cáo khoa học: Insulin/protein kinase B signalling pathway upregulates metastasis-related phenotypes and molecules in H7721 human hepatocarcinoma cell line pptx

... typical growth factor signalling pathway, such as receptor protein tyrosine kinase/ growth factor receptor binding protein 2-son of sevenless protein/ Ras/Raf/mitogen activated protein kinase kinase/mitogen ... activated protein kinase pathway [13]. Another function of the PKB signalling pathway is the promotion of cell survival or inhibition of cell apoptosis...

Ngày tải lên : 21/02/2014, 00:20

11
615
0

Tài liệu Báo cáo khoa học: Prion protein library of recombinant constructs for structural biology docx

... [26] for the numeration used in this article). This C-terminal fragment forms a globular domain both as part of the full-length sequence and in the isolated form, and there- fore constructs of ... sequence of the mature cellular form of the prion protein from a variety of species and truncated variants thereof, and of human doppel. The protein accession number refers to the...

Ngày tải lên : 18/02/2014, 08:20

9
458
1

Tài liệu Báo cáo khoa học: Multisite protein phosphorylation – from molecular mechanisms to kinetic models pdf

... 3187 providing additional mechanisms for the generation of activation thresholds. This is particularly true for dis- tributive kinetics (with multiple binding ⁄ dissociation events for kinase or phosphatase), ... Dalby KN (2001) The kinetic mechanism of the dual phosphorylation of the ATF2 transcription factor by p38 mitogen-activated protein (MAP) kinase a. Implic...

Ngày tải lên : 18/02/2014, 08:20

22
519
0

Tài liệu Báo cáo khoa học: SREBPs: protein interaction and SREBPs Ryuichiro Sato doc

... ligase (E3) required for the ﬁnal reaction of SREBP ubiquitination is a complex consisting of Skp1, Cul1, Rbx1, and one of a family of F-box proteins, Fbw7 [17]. Glycogen syn- thase kinase- 3b phosphorylates ... to growth factor stimuli [21]. This implies that growth factor stimuli interfere with sumoylation, thereby enhancing SREBP transcriptional activities, and lipid s...

Ngày tải lên : 18/02/2014, 13:20

6
589
1

Tài liệu Báo cáo khoa học: Antioxidant protein 2 prevents methemoglobin formation in erythrocyte hemolysates doc

... mouse). As the same protein is supposed to have the same name in diﬀerent species, we will use the old name of antioxidant protein 2 until this nomenclature issue is resolved by the human and mouse nomenclature ... transferred to new medium. Production of recombinant protein was induced by addition of isopropyl-b- D -thiogalactopyranoside. Cells were harvested, disrupted...

Ngày tải lên : 20/02/2014, 23:20

8
291
0

Tài liệu Báo cáo khoa học: TMPRSS13, a type II transmembrane serine protease, is inhibited by hepatocyte growth factor activator inhibitor type 1 and activates pro-hepatocyte growth factor pdf

... sequence analysis of the cDNA for a human serine protease responsible for activation of hepatocyte growth factor – structural similarity of the protease precursor to blood coagulation factor XII. ... representation of the structure of the full-length HAI-2 (1) and a soluble form of HAI-2 tagged at the C-terminals with myc-His (2). (C) Dose dependence of the inhibitor...

Ngày tải lên : 15/02/2014, 01:20

13
641
0

Tài liệu Báo cáo khoa học: Helicobacter pylori acidic stress response factor HP1286 is a YceI homolog with new binding speciﬁcity pdf

... a two-fold axis, all of the inter- actions reported below are repeated twice; that is, if Ala25 of chain A is close to Asn77 of chain B, then Asn77 of chain A is close to Ala25 of chain B. Chain ... is shorter with respect to that of the two homologous proteins whose structure has been determined: its volume is 151 A ˚ 3 , whereas that of the T. thermophilus protein...

Ngày tải lên : 16/02/2014, 14:20

10
768
0

Tài liệu Báo cáo khoa học: Collagen I regulates matrix metalloproteinase-2 activation in osteosarcoma cells independent of S100A4 pdf

... similarities of tissue inhibitor of metalloproteinases-2 and tissue inhibitor of metalloproteinases-1. Biochem J 278, 179–187. 16 DeClerck YA, Yean TD, Lu HS, Ting J & Langley KE (1991) Inhibition of ... soft structures of connective tissue. Collagens are the main components of ECM, and type I collagen is the most abundant form in bone and connective tissue [1]. Controll...

Ngày tải lên : 18/02/2014, 11:20

12
572
0

Tài liệu Báo cáo khoa học: A novel coupled enzyme assay reveals an enzyme responsible for the deamination of a chemically unstable intermediate in the metabolic pathway of 4-amino-3-hydroxybenzoic acid inBordetellasp. strain 10d doc

... Murakami 2 and Kenji Aoki 2 1 Division of Science of Biological Resources, Graduate School of Science and Technology, 2 Department of Biofunctional Chemistry, Faculty of Agriculture, Kobe University, ... peak of the puriﬁed enzyme at 266 nm. The typical protein absorption p eak of 2 80 nm shifts to 265 nm if the protein contains a ﬂavin-type cofac tor [28]. We failed to ide...

Ngày tải lên : 19/02/2014, 16:20

7
613
1