... Peptide Precursor B gene’s 5’-Flanking Region is Associated with Essential Hyper-tension among Japanese Females Kotoko Kosuge1, Masayoshi Soma1,3, Tomohiro Nakayama2, Noriko Aoi2, ... written informed consent for blood examinations from subjects not receiving medications. In the Japanese population, it has been reported that plasma BNP levels are positively associated with ... significantly more common in the EH group than in the NT group. These findings suggest that in Japanese individuals, this deletion in the NPRA gene reduces receptor activity and may confer increased...