Tài liệu Báo cáo khoa học: Investigation and prediction of the severity of p53 mutants using parameters from structural calculations pptx

Tài liệu Báo cáo khoa học: Investigation and prediction of the severity of p53 mutants using parameters from structural calculations pptx

Tài liệu Báo cáo khoa học: Investigation and prediction of the severity of p53 mutants using parameters from structural calculations pptx

... PREDMUT (PREDict MUTants) , was developed for prediction of the severity of p53 mutants. The method was trained on a set of known mutants and subsequently evaluated on another set. The method is based on parameters ... À yðÞ 2 q where x and y are values from the two parameters mea- sured, and x and y are the mean values for the respective parameters....
Ngày tải lên : 18/02/2014, 11:20
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Tài liệu Báo cáo khoa học: Osmosensing and signaling in the regulation of mammalian cell function docx

Tài liệu Báo cáo khoa học: Osmosensing and signaling in the regulation of mammalian cell function docx

... summarizes recent progress in the understanding of how osmosensing and osmosignaling integrate into the overall context of growth factor signaling and the execution of apoptotic programs. Abbreviations EGF, ... of the CD95 from inside the hepatocyte to the plasma mem- brane [39], which depends on a ROS-mediated tyrosine phosphorylation of the epidermal growth fac...
Ngày tải lên : 18/02/2014, 16:20
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Tài liệu Báo cáo khoa học: Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc docx

Tài liệu Báo cáo khoa học: Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc docx

... proceed with further biological testing of these compounds and the investigation of whether this pathway operates in the human body in vivo. Experimental procedures Preparation of enzymes Cytochrome ... the adre- nal gland may receive vitamin D from the bloodstream for further metabolism [4]. In conclusion, the identification of new metabolites of vitamin D3 made by...
Ngày tải lên : 18/02/2014, 17:20
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Tài liệu Báo cáo khoa học: Enzymatic and electron paramagnetic resonance studies of anabolic pyruvate synthesis by pyruvate: ferredoxin oxidoreductase from Hydrogenobacter thermophilus doc

Tài liệu Báo cáo khoa học: Enzymatic and electron paramagnetic resonance studies of anabolic pyruvate synthesis by pyruvate: ferredoxin oxidoreductase from Hydrogenobacter thermophilus doc

... Professor Hayao Taguchi (Tokyo University of Science) for the gift of the plasmid carry- ing the LDH gene from T. caldophilus; Dr Miho Aoshima and Ms Ayako Nishiyama for the preparation of the ... complete the cycle [6,7]. POR is one of the key enzymes of the reductive TCA cycle, and catalyzes the anabolic reduc- tive carboxylation of acetyl-CoA. Two [4Fe-4...
Ngày tải lên : 16/02/2014, 09:20
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Tài liệu Báo cáo khoa học: Diversity and junction residues as hotspots of binding energy in an antibody neutralizing the dengue virus doc

Tài liệu Báo cáo khoa học: Diversity and junction residues as hotspots of binding energy in an antibody neutralizing the dengue virus doc

... the numbering of the amino- acid sequences of immunoglobulins and the definition of their CDR loops, as described from 1997 [13]. The number- ing and definition of the L-CDR3 and H-CDR3 loops of mAb4E11 ... segment, and the V H -D, D-J H , and V L -J L junctions [17]. They are located at the center of the antibody combining site [18,19] and provide the...
Ngày tải lên : 19/02/2014, 07:20
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Tài liệu Báo cáo khoa học: "Names and Similarities on the Web: Fact Extraction in the Fast Lane" ppt

Tài liệu Báo cáo khoa học: "Names and Similarities on the Web: Fact Extraction in the Fast Lane" ppt

... How- ever, the matching of the part -of- speech tags of the sentence sequences to the left and right of the in- fix, against the part -of- speech tags of the seed fact, only succeeds for the last three ... outer boundaries of the fact are computed separately for the beginning of the first (left) and end of the sec- ond (right) phrases of the candida...
Ngày tải lên : 20/02/2014, 12:20
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Tài liệu Báo cáo khoa học: Unfolding and aggregation during the thermal denaturation of streptokinase pptx

Tài liệu Báo cáo khoa học: Unfolding and aggregation during the thermal denaturation of streptokinase pptx

... character- ization of the thermally induced aggregation of SK using a variety of techniques. The results provide us with some of the properties of these high molecular mass aggregates and help to delimit the ... number of two-state transitions. In these fittings the heat capacity change, DC p ,forthe unfolding of each domain was fixed by using the values obtained...
Ngày tải lên : 21/02/2014, 03:20
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Tài liệu Báo cáo khoa học: "Some Pragmatic Issues in the Planning of Definite and Indefinite Noun Phrases" potx

Tài liệu Báo cáo khoa học: "Some Pragmatic Issues in the Planning of Definite and Indefinite Noun Phrases" potx

... preconditions of this action depend strictly on the mutual belief of the speaker and the hearer at the time of the utterance. The noun phrase in a sentence such aa (6) Use the same wrench ... action, the speaker and hearer mutually know of a plan that will result in identification of the intended referent, and in the case of the S[ action, the...
Ngày tải lên : 21/02/2014, 20:20
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Tài liệu Báo cáo khoa học: Chemical approaches to mapping the function of post-translational modifications ppt

Tài liệu Báo cáo khoa học: Chemical approaches to mapping the function of post-translational modifications ppt

... inflammation [17], and immune response [11,12]. The study of these events is taxing, as the biosynthesis of glycoproteins is not tem- plate driven. This results in the formation of so-called ‘glycoforms’ ... University of Oxford, UK Introduction Post-translational modifications (PTMs) of proteins modulate protein activity and greatly expand the diver- sity and complexity...
Ngày tải lên : 18/02/2014, 17:20
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Tài liệu Báo cáo khoa học: An intermediate step in the evolution of ATPases – a hybrid F0–V0 rotor in a bacterial Na+ F1F0 ATP synthase pdf

Tài liệu Báo cáo khoa học: An intermediate step in the evolution of ATPases – a hybrid F0–V0 rotor in a bacterial Na+ F1F0 ATP synthase pdf

... handedness, and two of the rings face in the opposite direction in the membrane to the other two, forming the same pattern as in the AFM surface representation of Fig. 2A. By comparison with the ... By comparison with the 3D structure of the I. tartaricus c ring [24], the black rings represent the view from the cytoplasm (open rings in AFM) and the red on...
Ngày tải lên : 18/02/2014, 17:20
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