Tài liệu Báo cáo khoa học: The PA-TM-RING protein RING ﬁnger

Tài liệu Báo cáo khoa học: The PA-TM-RING protein RING ﬁnger protein 13 is an endosomal integral membrane E3 ubiquitin ligase whose RING ﬁnger domain is released to the cytoplasm by proteolysis ppt

... endosomal membranes pos- sess an E3 ubiquitin ligase that can be released into the cytoplasm by proteolysis. The PA-TM -RING protein RNF13 is synthesized as an integral endosomal membrane protein, ... Incorporation of the RING domain into an integral membrane protein allows the E3 activity to be spatially regulated. Presumably, the TM...

Ngày tải lên : 18/02/2014, 08:20

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Tài liệu Báo cáo khoa học: The unique sites in SulA protein preferentially cleaved by ATP-dependent Lon protease from Escherichia coli ppt

... regulatory mechanism of SulA might a lso e xist in other e nterobacteria. It is a lso an interesting issue to see whether such a mechanism exists in other proteolytic regulatory systems, such as the ... appeared to be relatively preferred at the P 1 sites. On the other hand, the cleavage in the absence of ATP was very much slower, especially in the central region, than in...

Ngày tải lên : 21/02/2014, 03:20

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Tài liệu Báo cáo khoa học: The tandemly repeated domains of a b-propeller phytase act synergistically to increase catalytic efﬁciency doc

... they can increase the amount of available phosphate by interacting together. Additionally, fusing PhyH-DI to a single -domain phytase appears to be an efﬁcient way to improve the activity of the ... greater than the activity sum of PhyH-DI and PhyH-DII and two times greater than that of PhyH- DII. This large variance cannot be ascribed to the function of PhyH-DI alone....

Ngày tải lên : 14/02/2014, 15:20

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Tài liệu Báo cáo khoa học: The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases docx

... confers resistance to the bacterial pathogen P. syringae pv tomato carrying the avirulence effector proteins AvrPto or AvrPtoB [17,18]. The OXI1 protein kinase was also shown to be an upstream regulator ... blot analysis using an anti-HIS or an anti-GST IgG. Figure 1C shows HIS-PTI1-4 and HIS-OXI1 bound to GST-OXI1 and GST-PTI1-4, respectively, but not to GST alone. The...

Ngày tải lên : 14/02/2014, 19:20

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Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf

... the cell cycle (Fig. 1). Cyclins B1 and B2 appear in S phase and accumulate in G 2 and mitosis before disappearing at the transition from metaphase to anaphase. Synthe- sis is controlled at the ... Mo ¨ ssner J, Mantovani R & Engeland K (2003) Cyclin B1 transcription is enhanced by the p300 coacti- vator and regulated during the cell cycle by a CHR-dependent repression...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: 3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-c-dependent and mediated by the caspase-3-dependent apoptotic pathway doc

... adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-c-dependent and mediated by the caspase-3-dependent apoptotic pathway Yuanyuan Xiao, Taichang Yuan, Wenqi ... However, owing to the remarkable ability of adipocytes to resist apoptosis, adipocyte apoptosis is much less studied and is poorly understood. Recently, evidence from seve...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid ppt

... Maintaining the balance between cell survival and apoptosis is critical in the maintenance of a healthy organism, and tipping the equilibrium in one or another direction results in either Keywords apoptosis; ... cell sensitivity to apoptotic signals [14,15]. The Bcl-2-homology domain- 3 (BH3)-only protein Bid is an abundant proapoptotic protein of the Bcl-2 family that...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: The plasminogen activator inhibitor 2 transcript is destabilized via a multi-component 3¢ UTR localized adenylate and uridylate-rich instability element in an analogous manner to cytokines and oncogenes pdf

... GM-CSF and IL-8, amongst others (Fig. 9) [28,29,33], and appear to function via similar mechanisms. Of greatest relevance to the PAI-2 ARE is the c-fos multidomain class I ARE, for which the structure ... combined and equally seeded into ﬁve 35 mm to ensure equal transfection efﬁciency within samples and the plates were returned to the incubator for further incubation. In...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc

... appears to be the main nuclear import determinant within the RS domain because the mutant lacking this motif (DRS1) accumulated in the cytoplasm. By contrast, ASF ⁄ SF2 nucleo-cytoplasmic distribution ... activity is encountered by the ability of TIAR to assemble abortive pre-initiation complexes coalescing into cytoplasmic granules called stress granules. To elucidat...

Ngày tải lên : 16/02/2014, 15:20

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Tài liệu Báo cáo khoa học: The two Caenorhabditis elegans metallothioneins (CeMT-1 and CeMT-2) discriminate between essential zinc and toxic cadmium docx

... four- coordinate rather than six-coordinate, or may reﬂect a larger than normal error in the EXAFS distance due to weaker scattering of the oxygen than of the sulfur, making the Cd–O contribution to the total ... possible to distin- guish between N ⁄ O ⁄ F or between P ⁄ S ⁄ Cl as a scatterer, the difference between O and S is substantial. Therefore, these data suggest tha...

Ngày tải lên : 16/02/2014, 15:20

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