... Okada, M., Tsujikawa, M., Shimomura, Y.,Nishida, K., Inoue, Y., Watanabe, H., Maeda, N., Kurahashi, H.,Kinoshita, S., Nakamura, Y. & Tano, Y. (1998) A kerato-epi-thelin (beta ig-h3) mutation ... explain the corneal involve-ment in other forms of amyloidosis [26]. In summary, autosomal dominant corneal diseases linkedto mutations in the BIGH3 gene are a prominent cause of corneal blindness ... presented anintermediate degree of amyloid fibril formation.Cysteine has the capacity to form disulfide bonds. Asdisulfide bonding of the protein may participate in theappearance of aggregates and...